Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Critically ill COVID-19 patients experience novel platelet-activating immune complexes, study finds

Canadian researchers from McMaster University, Ontario, have pinpointed platelet activating immune complexes in coagulation disorders associated with coronavirus disease 2019 (COVID-19), the condition caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

10 Nov 2020

Severe COVID-19 linked to age, body mass index and ABO blood group

With the COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infecting over 50 million people worldwide with hundreds of thousands experiencing severe respiratory illness, researchers have been trying to find the factors associated with severe disease. From the start of the pandemic in March this year, several studies have indicated heart disease, high blood pressure, diabetes, obesity, etc. could be linked to severe disease. Now German researchers have published a study on the association between severe respiratory infection caused by SARS CoV-2 and factors such as age, body mass index (BMI) and ABO blood group.

10 Nov 2020

Identifying SARS-CoV-2 spike protein mutations resistant to antibodies

Using a set of different monoclonal antibodies, researchers determined different mutations in the SARS-CoV-2 spike protein that leads to resistance. Understanding these resistant mutations is important in developing effective therapeutic strategies.

10 Nov 2020

Exosome-mediated mRNA delivery generates broad immune response to multiple SARS-CoV-2 proteins

Recently, researchers from The Johns Hopkins University School of Medicine, Baltimore, MD, USA, and Capricor Therapeutics, Inc., Beverly Hills, CA, USA, described a new approach to SARS-CoV-2 vaccine development using exosomes to deliver mRNAs that encode the antigens from multiple structural proteins of the virus.

9 Nov 2020

After SARS-CoV-2 antibodies fade B and T-cells persist

Now, an international team of thirty researchers from Sweden, Italy, Germany, the USA, and China aimed to determine the longevity of the immune response against SARS-CoV-2, particularly the specific memory B-cell and T-cell responses over time in convalescent COVID-19 patients.

9 Nov 2020

Aspirin to be tested as a potential COVID-19 treatment as part of RECOVERY trial

Now, in new research, the everyday painkiller aspirin will be evaluated as a potential treatment for COVID-19 in one of the United Kingdom’s most significant trials, aiming to evaluate whether it can reduce the risk of blood clots in infected people.

9 Nov 2020

Research explores links between Alzheimer's and Parkinson′s to COVID-19

In a recent medRxiv* preprint paper, Dr. L. Miguel Martins and colleagues from the University of Cambridge investigate the links between neurodegeneration and COVID-19.

9 Nov 2020

Heart rate data from wearable devices helps predict SARS-CoV-2 infection

A team of scientists from the Icahn School of Medicine at Mount Sinai in the United States has developed a digital platform to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and related symptoms in healthcare personnel.

9 Nov 2020

Study suggests herd immunity to COVID-19 in New York City is low

Researchers in the United States have estimated that the proportion of people in New York City who developed antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the first wave of the coronavirus disease 2019 (COVID-19) pandemic is around one in eight.

9 Nov 2020

Promising yeast-expressed SARS-CoV-2 vaccine candidate effective in mice

Researchers at the Texas Children's Hospital Center for Vaccine Development, USA, have published a report on the preprint server bioRxiv that describes a yeast-expressed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain (RBD) protein, a key target of current vaccine development efforts.

9 Nov 2020

Translational study within SARS-CoV-2 infected cells opens up new therapeutic avenues

A recent study published on the preprint server bioRxiv in October 2020 shows what the protein translation process looks like in specific terms. In doing so, the study has provided new insights that might prove helpful in developing new therapies for COVID-19 patients.

9 Nov 2020

ACE2 and TMPRSS2 not the only virus-receptors to mediate SARS-CoV-2 entry

However, a recent study published on the preprint server bioRxiv in November 2020 uncovers the major role played by the N-terminal domain of the SARS-CoV-2 virus in host infection. This could be of great use in measuring the usefulness of antibodies used in convalescent plasma therapy for COVID-19.

9 Nov 2020

Study of SARS-CoV-2 antibodies in >5,000 healthcare workers

To address this, Daniel J Cooper and his team of researchers conducted a prospective seroepidemiological study to systematically evaluate specific risk factors for healthcare workers. They used a SARS-CoV-2 immunoassay and analyzed the risk factors for seropositivity using multivariate logistic regression.

9 Nov 2020

Majority of population likely has pre-existing immunity to SARS-CoV-2, claim researchers

A team of researchers has conducted a study suggesting that the majority of the global population is likely to have pre-existing T-cell immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the coronavirus disease 2019 (COVID-19) pandemic.

9 Nov 2020

Immune-evading variants can emerge in SARS-CoV-2, researchers warn

An international team of researchers has shown that a mutation within severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the coronavirus disease 2019 (COVID-19) – enables the pathogen to evade antibody-mediated immunity while maintaining replication fitness and increasing viral loads.

9 Nov 2020

Cooler temperatures in U.S. may increase COVID-19 cases: New modeling study

How temperature affects the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been a question asked since the pandemic's early days. Just like the flu, which has a substantial seasonal variation, it is believed that SARS-CoV-2 also may be affected by temperature.

9 Nov 2020

Successful containment of COVID-19 in a Brazilian archipelago

The team of researchers in May 2020, headed by Ligia Regina Franco Sansigolo Kerr and Prof Costa Mendes, aimed to discuss and report the various control measures taken by FNA authorities in order to reduce the spread of SARS-CoV-2 virus in the Fernando de Noronha Archipelago (FNA). Their research is published on the preprint server medRxiv.

8 Nov 2020

Study shows SARS-CoV-2 direct heart muscle cell infection, cell death, loss of contractility

In the study, published on the pre-print journal bioRxiv, the researchers revealed that SARS-CoV-2-infected EHTs manifested the typical characteristics of myocarditis or heart inflammation. These include the stimulation of immune cells, heart cell death, and decreased contractile force generation.

8 Nov 2020

Researchers compare rhesus and cynomolgus macaques for SARS-CoV-2 vaccine trials

A team of researchers at the Biomedical Primate Research Centre based in the Netherlands have aimed to determine the effects of the SARS-CoV-2 pathogen on these monkeys and, subsequently, whether they make good animal models for future research in the area.

8 Nov 2020

Study suggests honey and Nigella sativa expedites viral clearance in COVID-19 patients

A team of researchers from various institutes across Pakistan, Chile, Canada, and the USA recently conducted a clinical trial to investigate the potential effectiveness of a combination of honey and Nigella sativa (HNS) in treating COVID-19 patients. Their study is published on the preprint server medRxiv prior to the scientific peer review process.

8 Nov 2020

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Critically ill COVID-19 patients experience novel platelet-activating immune complexes, study finds

Severe COVID-19 linked to age, body mass index and ABO blood group

Identifying SARS-CoV-2 spike protein mutations resistant to antibodies

Exosome-mediated mRNA delivery generates broad immune response to multiple SARS-CoV-2 proteins

After SARS-CoV-2 antibodies fade B and T-cells persist

Aspirin to be tested as a potential COVID-19 treatment as part of RECOVERY trial

Research explores links between Alzheimer's and Parkinson′s to COVID-19

Heart rate data from wearable devices helps predict SARS-CoV-2 infection

Study suggests herd immunity to COVID-19 in New York City is low

Promising yeast-expressed SARS-CoV-2 vaccine candidate effective in mice

Translational study within SARS-CoV-2 infected cells opens up new therapeutic avenues

ACE2 and TMPRSS2 not the only virus-receptors to mediate SARS-CoV-2 entry

Study of SARS-CoV-2 antibodies in >5,000 healthcare workers

Majority of population likely has pre-existing immunity to SARS-CoV-2, claim researchers

Immune-evading variants can emerge in SARS-CoV-2, researchers warn

Cooler temperatures in U.S. may increase COVID-19 cases: New modeling study

Successful containment of COVID-19 in a Brazilian archipelago

Study shows SARS-CoV-2 direct heart muscle cell infection, cell death, loss of contractility

Researchers compare rhesus and cynomolgus macaques for SARS-CoV-2 vaccine trials

Study suggests honey and Nigella sativa expedites viral clearance in COVID-19 patients

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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