Life Science White Papers

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Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.

The best practices to enhance cell line development

The best practices to enhance cell line development

In this article, Sphere Fluidics discusses the best practices for enhancing cell line development and how to implement them in research and development.

From Sphere Fluidics 16 Mar 2023

Fast track antibodies: Identifying and isolating rare antibody-secreting cells effectively

Fast track antibodies: Identifying and isolating rare antibody-secreting cells effectively

In this article, Sphere Fluidics showcases a high-throughput method of effectively identifying and isolating rare cells that secrete antibodies.

From Sphere Fluidics 16 Mar 2023

Discussing proliferation, outgrowth, and cell viability in picodroplets

Discussing proliferation, outgrowth, and cell viability in picodroplets

Picodroplet technology has had a transformative effect on single cell analysis. This article delves into a few of the major issues encountered with picodroplets and how to potentially overcome them.

From Sphere Fluidics 16 Mar 2023

Achieving reliable single cell cloning through advanced microfluidics dispensing

Achieving reliable single cell cloning through advanced microfluidics dispensing

Single cells are valuable biological reagents, but production and cloning of them can be an issue. This article dives into a novel method of cloning through microfluidics.

From Sphere Fluidics 16 Mar 2023

Overcoming obstacles in biotherapeutic development

Overcoming obstacles in biotherapeutic development

In this article, Sphere Fluidics demonstrates how they overcome common obstacles in biotherapeutic development in order to enhance production.

From Sphere Fluidics 16 Mar 2023

Finding and isolating high-production clones with monoclonality

Finding and isolating high-production clones with monoclonality

Cell line development is a process that is critical to biopharmaceutical development. As cell lines must be cloned from a single cell progenitor to ensure consistency, it is thus important to be able to find and isolate high-producing clones.

From Sphere Fluidics 16 Mar 2023

Demonstrating how to verify CAR-T cell function in microfluidic picodroplets

Demonstrating how to verify CAR-T cell function in microfluidic picodroplets

In this article, Sphere Fluidics discusses how the high-throughput function verification of CAR-T cell function is achieved in microfluidic picodroplets and the implications this could have for immuno and cell therapy.

From Sphere Fluidics 16 Mar 2023

How to overcome the biggest challenges in cell line development

How to overcome the biggest challenges in cell line development

While cell line development technologies continue to improve, there are still numerous hurdles to overcome. This article discusses the biggest challenges in cell line development and how to overcome them.

From Sphere Fluidics 16 Mar 2023

High-throughput B cell screening with the Cyto-Mine®

High-throughput B cell screening with the Cyto-Mine®

High-throughput B cell screening is an incredibly useful tool in the development of therapeutic antibodies. It rapidly decreases lead discovery times and as such is an area of high interest.

From Sphere Fluidics 16 Mar 2023

Cyto-Mine®: Developing an improved hybridoma-based antibody discovery process

Cyto-Mine®: Developing an improved hybridoma-based antibody discovery process

In this article, Sphere Fluidics demonstrates how its Cyto-Mine® instrument has been crucial in the acceleration of hybridoma-based antibody discovery.

From Sphere Fluidics 16 Mar 2023

Single B cell screening: How it aids in antibody discovery

Single B cell screening: How it aids in antibody discovery

Streamlined antibody discovery processes are of paramount importance to therapeutic development, single B cell screening is a major part of this and thus an optimized, high-throughput process is incredibly useful.

From Sphere Fluidics 16 Mar 2023

Understanding small molecule transport across cell membranes

Understanding small molecule transport across cell membranes

In this article, Sartorius discusses the uptake of small molecules across cell membranes.

From Sartorius 13 Mar 2023

Evaluating instrument data integrity in a lab

Evaluating instrument data integrity in a lab

In this article, Sartorius discusses how to evaluate instrument data integrity in a lab and provides a checklist of important steps to cover.

From Sartorius 13 Mar 2023

Accelerating biotherapeutic development through novel picodroplet assays

Accelerating biotherapeutic development through novel picodroplet assays

Uniform picoliter volume droplets, also known as picodroplets, can be utilized as 'test tubes' for high-throughput bioassays. The utilization of picodroplets allows for novel bioassays to be used, thus aiding biotherapeutic development, cell therapy, genome editing, and more.

From Sphere Fluidics 3 Mar 2023

Are Respiratory Syncytial Virus (RSV) vaccines on the way?

Are Respiratory Syncytial Virus (RSV) vaccines on the way?

Respiratory Syncytial Virus (RSV) vaccines have long been a challenge to formulate, but recent developments hint that their breakthrough may be closer than previously thought.

From Virus - An ACROBiosystems Brand 1 Mar 2023

Manufacturing cell therapeutics through GMP-grade protein services

Manufacturing cell therapeutics through GMP-grade protein services

In this article, ACROBiosystems demonstrates how their GMP-grade protein services can aid in the manufacturing of cell therapeutics.

From ACROBiosystems 1 Mar 2023

Microfluidics: Big developments on the small scale

Microfluidics: Big developments on the small scale

At Pittcon, the emphasis will be placed on how microfluidics can improve bioanalysis and various innovative applications in life sciences. Read more here

From Pittcon 23 Feb 2023

10 common applications of live cell analysis in immunology

10 common applications of live cell analysis in immunology

In this article, Sartorius introduces 10 of the most common applications for live cell analysis in immunology, discussing their importance, methods, and more.

From Sartorius 20 Feb 2023

Assessing small molecule kinetics and affinity through SPR screening

Assessing small molecule kinetics and affinity through SPR screening

As fragment-based drug discovery becomes more popular, the ability to analyze small molecule kinetics and affinity is increasingly useful. This paper demonstrates how SPR screening can be utilized to analyze these parameters.

From Sartorius 10 Feb 2023

Making antibody-drug conjugate development more rapid through site-specific conjugation

Making antibody-drug conjugate development more rapid through site-specific conjugation

In this article, ACROBiosystems discusses how they apply site-specific conjugation methods in order to accelerate the development of novel antibody-drug conjugates, thus improving therapeutics and healthcare for all.

From ACROBiosystems 27 Jan 2023

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