Life Science White Papers

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Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.

Using IC-ICP/MS Method to Determine Organic and Inorganic Arsenic Species

Arsenic (As) is a metallic element that occurs naturally in soil and ores in the environment.

From Metrohm USA Inc. 4 Oct 2017

Validating Hits Through NMR as an Orthogonal Biophysical Method

Studied for over 35 years, Neurotensin is a peptide that plays the role of a hormone in the gut and acts as a neurotransmitter in the brain. It modulates brain function and has been implicated in several central nervous system disorders, notably Parkinson’s disease, schizophrenia, eating disorders, drug abuse, and even pain, cancer and inflammatory symptoms. Its pathway has therefore become an important drug target to treat neurological diseases.

From Bruker BioSpin - NMR, EPR and Imaging 3 Oct 2017

Using ICP/MS or ICP/OES Method for Detection of Dimethyl Thallium in Water Samples

The high toxicity of thallium (Tl) means this element is of significant environmental relevance.

From Metrohm USA Inc. 2 Oct 2017

Sectioning and Staining Large Brain Tissue for Neuroscience Research

The following article is the first of a three-part series on imaging large whole mount brain sections for neuroscience research.

From Huron Digital Pathology 28 Sep 2017

Ultra Trace Determination of Bromate in Drinking Water by Microbore Column IC and ICP/MS

The chemical compound bromate is formed when drinking water is disinfected through ozonation.

From Metrohm USA Inc. 27 Sep 2017

Multiplex Immunoassays vs Gold Standard Assay Techniques

Antibody assays are widely used in clinical diagnostics and also in the process of drug development. Gold standard assay techniques include the enzyme-linked immunosorbent assay (ELISA), western blotting, and radioimmunoassay techniques.

From Vitl Life Science Solutions 26 Sep 2017

Redox Speciation Analysis of Iron Using IC-ICP/MS Technique

Environmental behavior of iron, its absorption by human and animals and its storage and transport all depend on its oxidation state.

From Metrohm USA Inc. 25 Sep 2017

Analyzing Morphology of Plant Fibers using Scanning Electron Microscopy

Scanning electron microscopy (SEM), in the last several years, has made a major impact on different fields of biology research that are either associated with the physiology and anatomy of plants, or with the use of plant fibers in various industrial applications.

From Thermo Fisher Scientific Phenom-World BV 25 Sep 2017

Using Resting-State Functional MRI for Fine-Grained Mapping of Mouse Brain Functional Connectivity

The neuroimaging field has been revolutionized by the resting state functional MRI or rs-fMRI technique, (Biswal et al., 1995), highlighting a major shift towards the notion of combined whole brain functional networks in contrast to the process of identifying isolated functional brain regions triggered by some stimulus paradigm.

From Bruker BioSpin - NMR, EPR and Imaging 22 Sep 2017

Indirect Ultra Trace Determination of Aminopolycarboxylic Acids in Surface Water Using IC-ICP/MS

Recently, organic compounds such as biomolecules and pesticides have been analyzed using the IC-ICP/MS method.

From Metrohm USA Inc. 20 Sep 2017

Using microCT to Research Targeted Approaches to Triple-Negative Breast Cancer

Breast cancer is one of the most heavily researched diseases to date. Current statistics suggest that 1 in 8 US women will develop breast cancer within her lifetime. Approximately 250,000 new cases of invasive breast cancer and 63,000 causes of non-invasive breast cancer diagnoses are estimated to occur in the US during 2017.

From Bruker BioSpin - NMR, EPR and Imaging 19 Sep 2017

Metrohm’s Vision Air Pharma Software Meets Technical Requirements of FDA CFR Part 11 for NIR Spectroscopy

Many criteria can be used to evaluate the prosperity of a society and the focus certainly differs depending on the individual.

From Metrohm USA Inc. 18 Sep 2017

Metrohm NIRS Solutions and Software Enable Pharmaceutical Analyses that Comply with Common Regulations

Common pharmacopoeias acknowledge NIRS as a secondary method for non-destructive, reliable and rapid analysis in pharmaceutical manufacturing.

From Metrohm USA Inc. 14 Sep 2017

Using NMR and MD Simulation to Study Helicity in IDPs

Since the turn of the century, scientists have been presenting evidence that contradicts previous understanding that all functional proteins have a specific, stable, three-dimensional structure. Research has shown that certain active proteins are at least partly intrinsically disordered in solution.

From Bruker BioSpin - NMR, EPR and Imaging 14 Sep 2017

Non-Invasive Diagnosis and Monitoring of Diabetes Mellitus

Diabetes, also known as diabetes mellitus, is a chronic metabolic disorder that affects roughly 8.5% of the world’s population, i.e., over 420 million people.

From Avantes BV 13 Sep 2017

Studying the Effects of Light and Color Perception in Fish Speciation

Researchers from the field of natural sciences, find spectroscopy as an important investigatory tool.

From Avantes BV 13 Sep 2017

Determination of Chromium Species in Soil and Pharmaceuticals by IC-ICP/MS Method

Chromium species can occur in a number of oxidation states, but – Cr(III) and Cr(VI) – the trivalent and hexavalent oxidation states are the most common.

From Metrohm USA Inc. 12 Sep 2017

VIAFLO ASSIST Automates Early Stage Cell-Based Assay Development

A video by INTEGRA shows how biotech contract research specialist Likarda LLC is using VIAFLO ASSIST to develop low-cost, high throughput, cell-based assays.

From INTEGRA Biosciences 12 Sep 2017

Piezo Actuators, Transducers, and Motor Drive Solutions for Medical Engineering and Life-Science Disciplines

Motion and positioning devices play an integral role in the life-science and medical engineering fields, fulfilling their many different requirements. The spectrum extends from simple low-energy drive components to ultrasonic transducers through to ultra-fast actuators and high-precision positioning systems for pumping and valve applications. These requirements are addressed by motor drives and piezoceramic transducers, which are known to have a long track record of ruggedness and reliability in optical technologies and semiconductor manufacturing industries.

From Physik Instrumente 8 Sep 2017

Hexapod 6-Axis Platform Helps Address Challenges in Biomechanical Metrology

Hexapod motion and positioning platforms are flexible based on a programmable center of rotation and can deliver precision motion in all degrees of freedom, making them the mainstream equipment for use in optics, physics, and engineering applications. As hexapods turn out to be more mainstream, they find their use in the medical field as well.