Sino Biological is a global leader in recombinant technology and manufactures exceedingly high-quality and hard-to-express proteins.
With the availability of proprietary expression platforms, high-throughput and scale-up capacities, and more than 15 years of experience, Sino Biological has successfully developed targets of interest from gene synthesis to protein characterization, regardless of a project's complexity.
Why choose Sino Biological?
Proprietary technologies
- Proprietary expression vectors, culture media, transfection reagents, etc.
Fast turnaround
- 12 Days: from gene synthesis to 100 mg eukaryotic protein production
High-throughput and Scale-up
- 1,000+ proteins available for every batch
- Flexible production scales: μg–kg level
- 80+ bioreactors: 2 to 1500 L
Multiple expression systems
Customized QC options
- SDS-PAGE, HPLC-SEC, UV, Endotoxin Test, ELISA, MS, Activity, etc.
Case study
Generating a protein with correct oligomeric status
- Active format: homo-dimmer
- Expression system: HEK293 cells
- Results: >95% dimerization and enhanced activity
- Strategy: initiating a molecular chaperone to streamline protein assembly
- Challenge: primarily exists as a monomer even following incubation → Low activity
Dimmer content
Image Credit: Sino Biological Inc.
Activity
Source: Sino Biological Inc.
| Sample |
Activity (Unit) |
| No chaperone, 0 hr |
200 |
| No chaperone, 48 hr |
800 |
| W/ chaperone, 0 hr |
4000 ↑ |
Purity
Image Credit: Sino Biological Inc.